Current Research Projects
Stationary CT
The project aims to develop a fixed-gantry CT scanner using multiple CNT x-ray source arrays and detectors
Example CT images
Selected publications
- "Evaluation of carbon nanotube x-ray source array for stationary head computed tomography" D. Spronk, et al. Medical Physics 48 (3), 1089 (2001).
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- "A stationary head CT prototype with CNT x-ray source arrays", D. Spronk et al. Medical Imaging 2022: Physics of Medical Imaging 12031, 597
3D Mammography
We demonstrated a stationary digital breast tomosynthesis scanner that can increase the system resolution and scan speed, and reduce the radiation dose
Selected publications
- "Initial clinical experience with stationary digital breast tomosynthesis", YZ Lee, et al., Academic Radiology, 2019
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-Visualizing micro calcification in lumpectomy specimens: an exploration into the clinical potential of carbon nanotube-enabled stationary digital breast tomosynthesis", C. Puett, et al. Biomedical physics & engineering express, 2019
Volumetric CT
We develop technologies to mitigate the limitations of the current CBCT scanners for 3D volumetric imaging
Selected publications
- "Feasibility of dual-energy CBCT by spectral filtration of a dual-focus CNT x-ray source", B. LI, et al. PlosOne 2022
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- "Volumetric computed tomography with carbon nanotube x-ray source array for improved image quality and accuracy", S. Xu et al., CommsEng, 2023
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Microbeam radiation therapy (MRT)
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MRT is an experimental radiotherapy technique with the potential of eradicating tumor while sparing normal tissues in small animal studies. We aim to develop an image guided bench-top microbeam irradiator for studying to MRT using small animal models.
Selected publications
-"immune-mediated effects of micro planar radiotherapy with a small animal irradiator", S. Bazaar, et al. Cancer, 2021
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-"Neurocognitive sparing of desktop microbeam irradiation:, S. Bazyar, Radiation Oncology, 2017
Intraoral tomosynthesis
To provide an improved visualization and diagnosis of dental diseases compared to 2D radiography. A prototype is being evaluated clinically at the UNC dental clinic.
From lab research to FDA clearance and clinical translation
Selected publications
-"Applying synthetic radiography to intraoral tomosynthesis: a step towards achieving 3D imaging in the dental clinic", C. Puett et al, Dentomaxillofacial Radiology, 2021
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- "Characterization and preliminary imaging evaluation of a clinical stationary intraoral tomosynthesis system", CR Inscoe et al, Medical Physics, 2018
Orthopedic imaging
We aim to develop a compact tomosynthesis scanner fro extremity imaging using the CNT x-ray source array technology
Selected publications
-"Point-of-care tomosynthesis imaging of the wrist", CR Inscoe et al,, Military Medicine 2021
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-"Preliminary imaging evaluation of a compact tomosynthesis system for potential point-of-care extremity imaging", CR Inscoe, et al., Medical Imaging 2020